It's been nearly 2 weeks since my last Lupron shot. I continue to be surprised that the side effects are different each time. With the shot before this, it took a week or more for any side effects to surface. This time it only took a couple days.
Last time I had hot flashes and the chills pretty regularly. Even more regular was mild nausea – not enough to feel really “sick”, just enough to ruin my day. Depression was also an issue, but it didn't set in until about three weeks after the shot. Now I'm only experiencing infrequent hot flashes and very infrequent chills – yah! My oncologist, as well as, my GP suggested I take Prilosec every morning as a prophylactic for the nausea. So far it's working great. The main area where I'm not doing better is with depression. It started much sooner than before and is very time sensitive, oddly enough. It starts when I wake up and lasts into the early evening most days. The latter part of the evening I'm fine. Very weird.
On balance it seems my body may be adapting to better handle the hot flashes and chills. The Prilosec is a super score on the nausea front. I hope the depression will subside. I find it so hard to motivate myself to do anything when it hits. Regardless, I feel lucky for the progress so far.